TABLE 2.
Parameter | Patients (n) | CEACAM1 Median (P25, P75) | Expression patterns | ||
---|---|---|---|---|---|
Membranous | Cytoplasmic | Negative | |||
Patient number | 80 (100.0) | 5.00 (4.00, 6.00) | 24 | 52 | 4 |
Gender | |||||
Male | 64 (80.0) | 6.00 (4.25, 7.00) | 16 | 45 | 3 |
Female | 16 (20.0) | 5.00 (3.00, 5.75) | 8 | 7 | 1 |
Age (years) | |||||
<60 | 49 (61.3) | 5.00 (4.00, 7.00) | 16 | 32 | 1 |
≥60 | 31 (38.8) | 6.00 (3.00, 6.00) | 8 | 20 | 3 |
Localization | |||||
Oropharynx | 17 (21.3) | 5.00 (4.00, 6.50) | 8 | 8 | 1 |
Oral cavity/Lip | 37 (78.8) | 6.00 (4.00, 6.50) | 11 | 25 | 1 |
Larynx | 17 (21.3) | 5.00 (4.00, 6.50) | 4 | 11 | 2 |
Hypopharynx | 9 (11.3) | 6.00 (4.00, 6.50) | 1 | 8 | 0 |
Histology | |||||
Well differentiated | 18 (22.5) | 4.50 (2.75, 6.00) | 11 | 5 | 2 |
Moderately differentiated | 47 (58.8) | 5.00 (5.00, 6.00) | 10 | 35 | 2 |
Poorly differentiated | 15 (18.8) | 6.00 (4.00, 7.00) | 3 | 12 | 0 |
T Classification | |||||
T1 | 23 (28.8) | 5.00 (4.00, 6.00) | 9 | 12 | 2 |
T2 | 25 (31.3) | 5.00 (3.50, 6.50) | 7 | 16 | 2 |
T3 | 9 (11.3) | 6.00 (5.00, 7.00) | 2 | 7 | 0 |
T4 | 23 (28.8) | 6.00 (5.00, 7.00) | 6 | 17 | 0 |
Lymph node metastasis | |||||
Negative (N0) | 49 (61.3) | 5.00 (3.00, 6.00) | 20 | 25 | 4 |
Positive (N1-3) | 31 (38.8) | 6.00 (5.00, 7.00) | 4 | 27 | 0 |
TNM stage | |||||
Ⅰ | 20 (25.0) | 5.00 (4.00, 6.00) | 8 | 10 | 2 |
Ⅱ | 13 (16.3) | 4.00 (2.50, 6.00) | 5 | 6 | 2 |
Ⅲ | 11 (13.8) | 6.00 (5.00, 6.00) | 4 | 7 | 0 |
Ⅳ | 36 (45.0) | 6.00 (5.00, 7.00) | 7 | 29 | 0 |
Tobacco smoking | |||||
Non-smoker | 28 (35.0) | 5.00 (3.25, 6.00) | 10 | 17 | 1 |
Smoker | 52 (65.0) | 5.50 (4.25, 6.75) | 14 | 35 | 3 |
Alcohol consumption | |||||
Non-drinker | 37 (46.3) | 5.00 (3.50, 7.00) | 12 | 23 | 2 |
Drinker | 43 (53.8) | 6.00 (4.00, 6.00) | 12 | 29 | 2 |
p16 status | |||||
Negative | 26 (32.5) | 5.00 (4.00, 6.00) | 9 | 15 | 2 |
Positive | 54 (67.5) | 6.00 (4.00, 7.00) | 15 | 37 | 2 |