Table 1.
MIC90, MFC and viability inhibition of miltefosine and voriconazole against Scedosporium and Lomentospora species.
| Miltefosine (μg/ml) | Voriconazole (μg/ml) | |||
|---|---|---|---|---|
| Growth inhibition (MIC90) | MFC | Growth inhibition (MIC90) | MFC | |
| Scedosporium aurantiacum | 4 | 4 | 1.25 | 1.25 |
| Scedosporium boydii | 2 | 2 | 0.31 | 0.62 |
| Scedosporium apiospermum | 4 | 4 | 1.25 | 2.5 |
| Scedosporium dehoogii | 4 | 4 | 0.625 | 0.625 |
| Lomentospora prolificans | 4 | 4 | 20 | 20 |
MIC90, Minimum inhibitory concentration that inhibits 90% of fungal growth.
MFC, minimum fungicidal concentration.
Experiments were performed in triplicate, in three independent experimental sets, to calculate the minimum inhibitory concentration (MIC).