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. 2021 Jan 23;11(7):1835–1852. doi: 10.1016/j.apsb.2021.01.015

Figure 1.

Fig. 1

G protein coupled receptor kinase 2 (GRK2) and prostaglandin E4 receptor (EP4) expression in synovial tissues (ST) of rheumatoid arthritis (RA) patients. (A) Representative micrographs of haematoxylin and eosin (HE)-stained histological sections of synovial tissues. The histology section shows the synoviocytes (S), the pannus (P), the inflammatory cells (I) (n = 8). Scale bars = 50 μm. (B) GRK2 and EP4 expression in synovial tissues paraffin section of RA patients were detected by immunohistochemistry (n = 8). Data are expressed as mean ± standard deviation (SD). #P < 0.05 vs. normal group. Arrows indicated the fibroblast-like synoviocytes (FLS) of RA. Scale bars = 50 μm. (C) GRK2 and EP4 expression in synovial tissues paraffin section of RA patients were detected by laser scanning confocal microscope (n = 8). Arrows indicated the FLS of RA. Scale bars = 25 μm. (D) GRK2/EP4 expression in synovial tissues frozen section of RA patients were detected by laser scanning confocal microscope (n = 8). Arrows indicated the FLS of RA. Scale bars = 25 μm.