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Antibacterial activities of all the lead new cyclic lipopeptides 2605-4 and 2612-8.1 are reported in comparison with colistin and vancomycin in μg/mL.
| Cyclic lipo-peptides (CLP) |
MIC 90 (μg/mL) |
||
| MRSA | P. aeruginosa | A. baumannii | |
| 2605-4 | 3.1–6.25 | >100 | 6.25–12.5 |
| 2612-8.1 | 12.5–25 | 12.5–25 | 6.25–12.5 |
| Colistin | >100 | *ND | <0.78 |
| Vancomycin | 12.5-25 | *ND | >100 |
*ND: Not determined.
