Table 1.
Demographic Characteristics of Individuals With Neuroimaging Data Available From the UK Biobank After Exclusions
| Demographic Characteristics | 15q11.2 BP1-BP2 CNVs |
Test Statistica | p Value | |||
|---|---|---|---|---|---|---|
| Deletion | NoCNV | Duplication | ||||
| UK Biobank | Total | 102 | 28,951 | 113 | ||
| Male, n (%) | 55 (54%) | 13,623 (47%) | 52 (46%) | χ22 = 1.97 | .37 | |
| Age, mean (SD); [range] | 55.4 (7.3); [40–68] | 54.9 (7.4); [40–70] | 54.8 (7.2); [40–69] | F2 = 0.42 | .5 | |
| deCODE (24) | Total | 30 | 19 | 27 | ||
| Male, n (%) | 14 (47%) | 12 (63%) | 12 (44%) | χ22 = 1.78 | .41 | |
| Age, mean (SD); [range] | 42.8 (12.5); [21–65] | 38.9 (10.6); [22–59] | 43.5 (13.5); [22–65] | F2 = 0.026 | .87 | |
See Methods and Materials for exclusion criteria. Details from the Icelandic sample (deCODE), used in our previous study (24), are shown for comparison.
CNV, copy number variant; NoCNV, no pathogenic CNVs.
a
Statistical differences in sex and age between each group (deletion, NoCNV, and duplication) were assessed using χ2 and analysis of variance, respectively.