Table 4.
Patient outcomes by induction agent used (n = 1260)
Outcome | Induction agent | p-value | ||
---|---|---|---|---|
Ketamine vs. etomidate | Ketamine vs. propofol | Etomidate vs. propofol | ||
In-hospital mortality | 1.5 (0.7, 3.0) | 3.2 (0.9, 11.9) | 4.7 (1.2, 18.5)* | 0.06 |
Hypotension 24 h post intubation | 1.4 (0.8, 2.4) | 1.2 (0.7, 2.2) | 1.6 (0.8, 3.3) | 0.36 |
Vasopressor requirement 24 h post intubation | 0.8 (0.4, 1.4) | 2.1 (1.1, 3.8)* | 1.5 (0.7, 3.3) | 0.07 |
Complication | 1.0 (0.6, 1.8) | 1.0 (0.6, 1.8) | 1.3 (0.7, 2.7) | 0.61 |
Discharged home with/without services | 1.7 (0.9, 3.1) | 0.9 (0.5, 1.7) | 1.5 (0.7, 3.2) | 0.22 |
Estimates represents OR (95% CI). All models are adjusted for hospital site, age, injury severity score (ISS), revised trauma score (RTS), traumatic brain injury (TBI), and intubation location
*Significantly different at a Bonferroni-adjusted p < 0.05