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. 2021 Aug 6;48(3):2275–2286. doi: 10.1007/s00068-021-01759-0

Table 4.

Patient outcomes by induction agent used (n = 1260)

Outcome Induction agent p-value
Ketamine vs. etomidate Ketamine vs. propofol Etomidate vs. propofol
In-hospital mortality 1.5 (0.7, 3.0) 3.2 (0.9, 11.9) 4.7 (1.2, 18.5)* 0.06
Hypotension 24 h post intubation 1.4 (0.8, 2.4) 1.2 (0.7, 2.2) 1.6 (0.8, 3.3) 0.36
Vasopressor requirement 24 h post intubation 0.8 (0.4, 1.4) 2.1 (1.1, 3.8)* 1.5 (0.7, 3.3) 0.07
Complication 1.0 (0.6, 1.8) 1.0 (0.6, 1.8) 1.3 (0.7, 2.7) 0.61
Discharged home with/without services 1.7 (0.9, 3.1) 0.9 (0.5, 1.7) 1.5 (0.7, 3.2) 0.22

Estimates represents OR (95% CI). All models are adjusted for hospital site, age, injury severity score (ISS), revised trauma score (RTS), traumatic brain injury (TBI), and intubation location

*Significantly different at a Bonferroni-adjusted p < 0.05