Skip to main content
. 2021 Aug 6;48(3):2275–2286. doi: 10.1007/s00068-021-01759-0

Table 5.

Patient outcomes by induction agent used (n = 1260)

Induction agent IRR (95% CI) p-value Predicted LOS/complication rate (95% CI)
ICU LOS
 Propofol Ref Ref 12.5 (9.0–16.0)
 Ketamine 0.9 (0.7–1.2) 0.49 11.3 (9.1–13.6)
 Etomidate 0.8 (0.6–1.1) 0.25 10.5 (9.6–11.3)
Total hospital LOS
 Propofol Ref Ref 20.0 (15.1–25.0)
 Ketamine 0.99 (0.8–1.3) 0.94 19.8 (16.0–23.6)
 Etomidate 0.8 (0.6–1.1) 0.15 16.3 (14.9–17.6)
Days on MV
 Propofol Ref Ref 6.9 (4.8–9.0)
 Ketamine 1.2 (0.9–1.6) 0.31 8.0 (6.3–9.7)
 Etomidate 1.1 (0.8–1.5) 0.68 7.4 (6.8–8.0)
Number of complications
 Propofol Ref Ref 1.0 (0.7–1.4)
 Ketamine 1.3 (0.9–1.8) 0.18 1.3 (1.0–1.6)
 Etomidate 1.7 (1.2–2.5) 0.008 1.7 (1.6–1.9)

By negative binomial regression. All models are adjusted for hospital site, age, injury severity score (ISS), revised trauma score (RTS), traumatic brain injury (TBI), and induction location. The NB model for complications was offset by the total length of stay (LOS)

ICU intensive care unit, LOS length of stay, MV mechanical ventilation