Table 6.

Patient outcomes by induction agent in patients with ISS > 16 (n = 664)

Outcome	Induction agent			p-value
	Ketamine vs. etomidate	Ketamine vs. propofol	Etomidate vs. propofol
In-hospital mortality	1.6 (0.8, 3.1)	4.3 (1.1, 16.5)*	6.8 (1.8, 25.3)*	0.003
Hypotension 24 h post intubation	1.0 (0.5, 1.9)	0.8 (0.4, 1.7)	0.8 (0.4, 1.7)	0.78
Vasopressor requirement 24 h post intubation	0.5 (0.3, 0.9)*	1.7 (0.8, 3.9)	0.8 (0.4, 2.0)	0.067
Complication	1.6 (0.8, 3.2)	1.7 (0.8, 3.7)	2.8 (1.2, 6.4)*	0.056
Discharged home with/without services	1.3 (0.6, 2.7)	1.0 (0.4, 2.2)	1.2 (0.5, 3.0)	0.78

Estimates represents OR (95% CI). All models are adjusted for hospital site, age, revised trauma score (RTS), traumatic brain injury (TBI), and intubation location

^*Significantly different at a Bonferroni-adjusted p < 0.05