Figure 3.

The visual acuity is impaired in 5xFAD mice at 6 months. (A) Illustration of the optokinetic system that measures the mouse visual acuity. Visual acuity is the maximum spatial frequency of the moving gratings that a mouse can track with its head movement. (B) Scattered plot of the visual acuity of 5xFAD and WT at 4 and 6 months. The visual acuity of 5xFAD was lower than that of WT both at 4 months and at 6 months, and the difference reached significance at 6 months. Data shown as mean ± SEM. *p < 0.05, two-way ANOVA.