Figure 2.

Luteolin (lut) improves visual behaviors in rd10 mice.

(A, C) Illustrations of apparatuses for dark-light transition (A) and optomotor tests (C). (B) Percentages of time during which mice stayed in the dark chamber (relative to the total duration of the test) at P25. (D) Visual acuity (the finest grating at which an animal shows an optomotor reflex) presented in the unit of cycle per degree (cpd). Luteolin treatment increased the duration rd10 mice spent in the darkness and their visual acuity. Data are expressed as mean ± SEM. ***P < 0.001 (one-way analysis of variance followed by Tukey’s post hoc test). Numbers in bars indicate quantities of mice tested. P: Postnatal day; PBS: phosphate-buffered saline; rd: rd10; WT: wild-type.