Figure 3.

Luteolin (lut) improves light responses in the retinas of rd10 mice.

(A, C) Representative electroretinogram (ERG) traces in response to light flashes under dark adaptation (scotopic 3.0 cd·s/m², A) and light adaptation (photopic 10.0 cd·s/m², C) from a WT (black lines) or rd10 mouse treated with PBS (gray lines) or luteolin (gray dotted lines) at P26. (B) Peak amplitudes (amp) of the scotopic a- and b-waves. (D) Peak amplitudes (amp) of photopic a- and b-waves. Data are expressed as mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001 (Student’s t-test). Numbers within bars indicate quantities of mice tested. P: Postnatal day; PBS: phosphate-buffered saline; rd: rd10; WT: wild-type.