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Volcano plots of the differentially expressed miRNAs in the APP/PS1 mouse cortices at 1 (A), 3 (B), 6 (C), and 9 months (D) of age, in contrast to the corresponding control ones.
Red triangles indicate up-regulated miRNAs, green triangles indicate down-regulated miRNAs, and purple dots indicate non-significant miRNAs. APP: Amyloid-beta peptide precursor protein; miRNA: microRNA; PS1: presenilin 1; WT: wild type.
