Additional Table 3.
Quality assessment of mRNA sequencing reads including total read counts, total bases counts, average read length, N bases count, N bases ratio, GC bases count, and GC bases ratio
| Sample | Total reads count | Total bases count (bp) | Average read length (bp) | N bases count (bp) | N bases ratio (%) | GC bases count (bp) | GC bases ratio (%) |
|---|---|---|---|---|---|---|---|
| 1-month-old WT control mice-1 | 40433196 | 5.86E+09 | 144.85 | 43096 | 0.00 | 2.77E+09 | 47.32 |
| 1-month-old WT control mice-2 | 43209168 | 6.13E+09 | 141.9 | 45392 | 0.00 | 2.9E+09 | 47.23 |
| 1-month-old WT control mice-3 | 45541384 | 6.48E+09 | 142.29 | 48381 | 0.00 | 3.04E+09 | 46.89 |
| 3-month-old WT control mice-1 | 39512610 | 5.56E+09 | 140.83 | 39412 | 0.00 | 2.62E+09 | 47.08 |
| 3-month-old WT control mice-2 | 41423302 | 5.94E+09 | 143.41 | 44123 | 0.00 | 2.8E+09 | 47.08 |
| 3-month-old WT control mice-3 | 39635208 | 5.6E+09 | 141.18 | 40906 | 0.00 | 2.62E+09 | 46.76 |
| 6-month-old WT control mice-1 | 47357382 | 6.55E+09 | 138.34 | 49728 | 0.00 | 3.08E+09 | 47.02 |
| 6-month-old WT control mice-2 | 53443434 | 7.49E+09 | 140.19 | 55815 | 0.00 | 3.49E+09 | 46.54 |
| 6-month-old WT control mice-3 | 48789418 | 6.9E+09 | 141.47 | 51248 | 0.00 | 3.2E+09 | 46.42 |
| 9-month-old WT control mice-1 | 59615552 | 8.48E+09 | 142.19 | 62858 | 0.00 | 3.97E+09 | 46.85 |
| 9-month-old WT control mice-2 | 39391226 | 5.61E+09 | 142.45 | 41892 | 0.00 | 2.62E+09 | 46.63 |
| 9-month-old WT control mice-3 | 48826638 | 6.83E+09 | 139.81 | 50966 | 0.00 | 3.22E+09 | 47.18 |
| 1-month-oldAPP/PS1 mice-1 | 57970216 | 8.27E+09 | 142.63 | 61252 | 0.00 | 3.91E+09 | 47.27 |
| 1-month-oldAPP/PS1 mice-2 | 50057628 | 7.12E+09 | 142.3 | 53171 | 0.00 | 3.32E+09 | 46.68 |
| 1-month-oldAPP/PS1 mice-3 | 40833668 | 5.88E+09 | 144.08 | 43147 | 0.00 | 2.77E+09 | 47.03 |
| 3-month-oldAPP/PS1 mice-1 | 45900922 | 6.56E+09 | 142.86 | 48482 | 0.00 | 3.13E+09 | 47.72 |
| 3-month-oldAPP/PS1 mice-2 | 56139412 | 7.97E+09 | 141.96 | 60656 | 0.00 | 3.81E+09 | 47.79 |
| 3-month-oldAPP/PS1 mice-3 | 49399086 | 7.02E+09 | 142.12 | 51967 | 0.00 | 3.34E+09 | 47.51 |
| 6-month-oldAPP/PS1 mice-1 | 57033794 | 8.15E+09 | 142.88 | 59119 | 0.00 | 3.83E+09 | 46.99 |
| 6-month-oldAPP/PS1 mice-2 | 50321498 | 7.08E+09 | 140.67 | 52788 | 0.00 | 3.34E+09 | 47.15 |
| 6-month-oldAPP/PS1 mice-3 | 49672972 | 7.02E+09 | 141.35 | 52578 | 0.00 | 3.31E+09 | 47.12 |
| 9-month-oldAPP/PS1 mice-1 | 45057550 | 6.33E+09 | 140.59 | 46942 | 0.00 | 2.98E+09 | 47.08 |
| 9-month-oldAPP/PS1 mice-2 | 46885262 | 6.6E+09 | 140.76 | 50649 | 0.00 | 3.14E+09 | 47.56 |
| 9-month-oldAPP/PS1 mice-3 | 47760514 | 6.73E+09 | 141 | 50270 | 0.00 | 3.17E+09 | 47.01 |
APP: Amyloid-beta peptide precursor protein; mRNA: messenger RNA; PS1: presenilin 1; WT: wild type.