Additional Table 5.
Summary of the genome mapping analysis in the mRNA sequencing, including total reads, total mapped, multiple mapped, and uniquely mapped
| 1-month-oldAPP/PS1 mice-1 | 57645074(100.00) | 56478112(97.98) | 5519333(9.57) | 50958779(88.40) |
|---|---|---|---|---|
| 1-month-oldAPP/PS1 mice-2 | 49838274(100.00) | 48690532(97.70) | 5341983(10.72) | 43348549(86.98) |
| 1-month-oldAPP/PS1 mice-3 | 40295096(100.00) | 39525994(98.09) | 4217821(10.47) | 35308173(87.62) |
| 3-month-oldAPP/PS1 mice-1 | 45610434(100.00) | 44815837(98.26) | 4333420(9.50) | 40482417(88.76) |
| 3-month-oldAPP/PS1 mice-2 | 55801684(100.00) | 54941587(98.46) | 5729908(10.27) | 49211679(88.19) |
| 3-month-oldAPP/PS1 mice-3 | 49198822(100.00) | 48355747(98.29) | 5016434(10.20) | 43339313(88.09) |
| 6-month-oldAPP/PS1 mice-1 | 56729808(100.00) | 55385310(97.63) | 5460583(9.63) | 49924727(88.00) |
| 6-month-oldAPP/PS1 mice-2 | 49936330(100.00) | 48688484(97.50) | 4828609(9.67) | 43859875(87.83) |
| 6-month-oldAPP/PS1 mice-3 | 49451032(100.00) | 48231136(97.53) | 4605643(9.31) | 43625493(88.22) |
| 9-month-oldAPP/PS1 mice-1 | 44749838(100.00) | 43833491(97.95) | 4274531(9.55) | 39558960(88.40) |
| 9-month-oldAPP/PS1 mice-2 | 46686074(100.00) | 45838689(98.18) | 4553327(9.75) | 41285362(88.43) |
| 9-month-oldAPP/PS1 mice-3 | 47340792(100.00) | 46355236(97.92) | 4974744(10.51) | 41380492(87.41) |
| 1-month-old WT control mice-1 | 40266824(100.00) | 39549660(98.22) | 3668373(9.11) | 35881287(89.11) |
| 1-month-old WT control mice-2 | 43046128(100.00) | 42128600(97.87) | 4130045(9.59) | 37998555(88.27) |
| 1-month-old WT control mice-3 | 45413022(100.00) | 44411874(97.80) | 4669144(10.28) | 39742730(87.51) |
| 3-month-old WT control mice-1 | 39355612(100.00) | 38467260(97.74) | 4047409(10.28) | 34419851(87.46) |
| 3-month-old WT control mice-2 | 41078916(100.00) | 40224216(97.92) | 4001573(9.74) | 36222643(88.18) |
| 3-month-old WT control mice-3 | 39473852(100.00) | 38615724(97.83) | 4270591(10.82) | 34345133(87.01) |
| 6-month-old WT control mice-1 | 46790578(100.00) | 45107760(96.40) | 4380712(9.36) | 40727048(87.04) |
| 6-month-old WT control mice-2 | 52953292(100.00) | 51121040(96.54) | 5162467(9.75) | 45958573(86.79) |
| 6-month-old WT control mice-3 | 48484678(100.00) | 47047494(97.04) | 5071495(10.46) | 41975999(86.58) |
| 9-month-old WT control mice-1 | 59390490(100.00) | 58072403(97.78) | 6034802(10.16) | 52037601(87.62) |
| 9-month-old WT control mice-2 | 39148440(100.00) | 38268847(97.75) | 4164961(10.64) | 34103886(87.11) |
| 9-month-old WT control mice-3 | 48615188(100.00) | 47541532(97.79) | 4866562(10.01) | 42674970(87.78) |
Data are expressed as number (percentage). APP: Amyloid-beta peptide precursor protein; mRNA: messenger RNA; PS1: presenilin 1; WT: wild type.