Table 1.
Top 10 of the most significantly dysregulated mRNAs in the AD mouse cortices at 1, 3, 6, and 9 months of age
| Gene ID | Gene name | log2 (fold-change) | P-value | Q-value | Result |
|---|---|---|---|---|---|
| ENSMUSG00000076036 | Gm22133 | 18.8115 | 1.63E-13 | 1.97E-10 | Up |
| ENSMUSG00000056054 | S100a8 | 16.81507 | 2.90E-05 | 0.002872 | Up |
| ENSMUSG00000081229 | Lamr1-ps1 | 17.08634 | 1.20E-17 | 1.55E-14 | Up |
| ENSMUSG00000104953 | AC147560.1 | 6.371299 | 1.62E-05 | 0.014659 | Up |
| ENSMUSG00000068129 | Cst7 | 7.094351 | 4.02E-102 | 7.04E-98 | Up |
| ENSMUSG00000000982 | Ccl3 | 7.058177 | 1.63E-23 | 2.38E-20 | Up |
| ENSMUSG00000056071 | S100a9 | 6.150368 | 8.08E-05 | 0.006578 | Up |
| ENSMUSG00000064220 | Hist2h2aa1 | –17.8056 | 2.38E-18 | 1.81E-15 | Down |
| ENSMUSG00000098974 | Gm27505 | –6.97485 | 2.16E-11 | 2.80E-08 | Down |
| ENSMUSG00000064365 | mt-Ts2 | –7.17382 | 1.68E-06 | 0.000251 | Down |
AD: Alzheimer’s disease.