TABLE 2.
Frequency distribution of CYP2D6 alleles in distinct populations according to Brazilian regions.
| Author | Brazilian region | Population | CYP2D6 allele frequencies | |||
|---|---|---|---|---|---|---|
| — | — | — | *2 | *4 | *10 | *41 |
| Silveira et al (2009a) | Southeast | Children LLA | — | 0.1316 | — | — |
| Silveira et al (2009b) | Southeast | Hospital | — | 0.0955–0.909 | — | — |
| Antunes et al. (2012) | Southern | Breast cancer | 0.1753 | 0.1443 | 0.0103 | 0.0412 |
| Friedrich et al (2014) | Four regions | Healthy | 0.215 | 0.094 | 0.0205 | 0.055 |
| Kohlrausch et al (2009) | Southern | Healthy | 0.125–0.1265 | 0.0632–0.1033 | 0.272–0.402 | 0.0707–0.1092 |
| Southern | Schizophrenic | 0.182 | 0.1318 | 0.215 | 0.833 | |
| Current study | Northern (5 areas) | P. vivax patients | 0.056–0.149 | 0.310–0.350 | 0.056–0.167 | 0–0.011 |
LLA–Acute Lymphoblastic Leukemia.