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. 2021 Jul 7;13(7):e16224. doi: 10.7759/cureus.16224

Table 5. Mean macular thickness in Parkinson’s disease patients and controls after controlling potential confounders.

aAdjusted mean using ANCOVA after controlling for gender, DM, and HPT (p < 0.05).

ANCOVA: analysis of covariance; DM: diabetes mellitus; HPT: hypertension

Macula Adj Mean Adj Mean Differences (95% CI) F-statistic (df) p-Valuea
Parkinson (95% CI) Controls (95% CI)
Average 266.51 (258.47, 274.54) 281.34 (273.31, 289.37) -14.83 (-26.68, -2.99) 6.143 (1, 123) 0.015
Centre 236.37 (228.53, 244.21) 255.55 (247.71, 263.40) -19.18 (-30.76, -7.61) 10.767 (1, 123) 0.001
Inner superior 311.39 (305.17, 317.61) 319.89 (313.67, 326.11) -8.50 (-17.68, 0.68) 3.361 (1, 123) 0.069
Inner inferior 308.85 (302.73, 314.96) 315.67 (309.56, 321.78) -6.82 (-15.84, 2.20) 2.242 (1, 123) 0.137
Inner nasal 315.53 (308.19, 322.87) 320.23 (312.99, 327.67) -4.80 (-15.63, 6.03) 0.769 (1, 123) 0.382
Inner temporal 299.41 (293.05, 305.77) 305.54 (299.18, 311.90) -6.13 (-15.52, 3.25) 1.674 (1, 123) 0.198
Outer superior 269.16 (264.32, 273.99) 278.19 (273.35, 283.02) -9.03 (-16.16, -1.90) 6.277 (1, 123) 0.014
Outer inferior 256.34 (251.89, 260.79) 272.24 (267.79, 276.69) -15.90 (-22.47, -9.34) 22.98 (1, 123) <0.001
Outer nasal 287.64 (281.58, 293.71) 302.84 (296.78, 308.91) -15.20 (-24.14, -6.26) 11.315 (1, 123) 0.001
Outer temporal 257.09 (250.62, 263.55) 263.40 (256.93, 269.86) -6.31 (-15.85, 3.23) 1.715 (1, 123) 0.193