Table 5.
Prevalence of autoantibodies in the two groups of patients with CHC, with or without TD
|
Autoantibodies |
Percentage of patients with autoantibodies present in those with TD |
Percentage of patients with autoantibodies present in those without TD |
Statistical test p-value |
|
CG |
35.71% (5/14 pts.) |
4.87% (4/82 pts.) |
<0.0001* |
|
RF |
42.85% (6/14 pts.) |
7.31% (6/82 pts.) |
<0.0001* |
|
ANA |
28.57% (4/14 pts.) |
8.53% (7/82 pts.) |
<0.0001* |
|
TPOAb |
100% (14/14 pts) |
0% |
<0.0001* |
|
TgAb |
78.57% (11/14 pts.) |
0% |
<0.0001* |
ANA: Antinuclear antibodies; CG: Cryoglobulins; CHC: Chronic hepatitis C; RF: Rheumatoid factors; TD: Thyroid disorder; TgAb: Antithyroglobulin antibodies; TPOAb: Anti-thyroid peroxidase antibodies. *Highly statistically significant