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One eye was assessed per participant. Aflibercept 2q16 group: intravitreal injection of aflibercept, 2 mg, every 16 weeks after 3 initial monthly doses and one 8-week interval. Aflibercept 2q8/PRN group: intravitreal injection of aflibercept, 2 mg every 8 weeks after 5 initial monthly doses, with pro re nata (PRN) dosing beginning at week 56. DRSS indicates Diabetic Retinopathy Severity Scale; NPDR, nonproliferative diabetic retinopathy; and PRN, pro re nata.
