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. 2021 Jul 21;143(30):11337–11344. doi: 10.1021/jacs.1c06287

Figure 2.

Figure 2

Scope of the indole-to-quinoline ring expansion. Conditions: 2 (1 equiv), 1 (3 equiv), Na2CO3 (3 equiv), CH3CN (0.1 M), 50 °C, 12 h. Isolated yields, 0.1–0.3 mmol scale. a5 equiv of 1. b48 h.