The total volume of the epidermis (A), dermis (B) and fibrous (C) tissue in PVA, H/PVA, H/PVA/E, and control group were compared. Hematoxylin and eosin-stained histopathological view of the wound (D) at day 7 (40 Ă— magnification). aP<0.005 vs. control group; bP<0.001 vs. PVA group