Table 1.
Characteristic | Neither individual nor sibling with LBW | Individual without LBW, sibling with LBW | Individual LBW, sibling not LBW | Individual and sibling with LBW |
---|---|---|---|---|
N total | 1,483,071 | 181,507 | 111,387 | 71,600 |
Mean number of siblings | 1.6 ± 0.8 | 1.9 ± 1.0a | 1.5 ± 0.7a | 1.7 ± 0.9a |
Mean number of years of follow-up | 28.4 ± 12.4 | 29.0 ± 12.2a | 29.2 ± 12.6a | 29.2 ± 12.4a |
Proportion with preterm birth | 1.5% | 2.6%a | 28.0%a | 28.1%a |
Proportion with SGA | 3.5% | 9.4%a | 60%a | 65%a |
Proportion with maternal preeclampsia | 2.1% | 2.7%a | 8.5%a | 8.1%a |
Proportion with 5-min Apgar score <7 | 0.7% | 0.6% | 2.6%a | 2.4%a |
Proportion with maternal diseaseb | 2.2% | 2.5%a | 2.7%a | 3.4%a |
Form of kidney disease | ||||
N with chronic kidney disease | 2413 | 388a | 326a | 209a |
N with acute kidney disease | 2499 | 368a | 275a | 185a |
N with glomerulonephritis | 2666 | 375c | 245c | 177a |
N with hereditary cystic kidney disease | 706 | 109c | 70c | 49c |
N with kidney or urinary tract malformations | 2065 | 23 | 193b | 152a |
LBW, low birth weight; SGA, small for gestational age.
P < 0.001.
Maternal disease was defined as maternal diabetes mellitus, kidney disease, rheumatic disease, or essential hypertension diagnosed before pregnancy.
P < 0.01 as compared with the group with neither individual nor sibling with LBW.