Table 1.
Study Population Characteristicsa
| Characteristic | Total (N = 107,962) | ACR Measurement Available Within 1 Year (n = 39,476) | ACR Measurement Unavailable Within 1 Year (n = 68,486) |
|---|---|---|---|
| Index eGFR (ml/min/1.73 m2), mean (SD) | 45.34 (10.41) | 44.22 (10.48) | 45.99 (10.31) |
| Age (yrs), median (IQR) | 79.52 (72.58-85.24) | 78.59 (71.94-84.09) | 79.93 (72.86-85.75) |
| Male | 46,310 (42.89) | 18,752 (47.50) | 27,558 (40.24) |
| BMI categories | |||
| Underweight (<18.5 kg/m2) | 1770 (1.64) | 435 (1.10) | 1335 (1.95) |
| Normal weight (18.5-25 kg/m2) | 27,387 (25.37) | 8601 (21.79) | 18,786 (27.43) |
| Overweight (25-30 kg/m2) | 39,452 (36.54) | 14,602 (36.99) | 24,850 (36.28) |
| Obese (>30 kg/m2) | 35,513 (32.89) | 15,077 (38.19) | 20,436 (29.84) |
| Missing | 3840 (3.56) | 761 (1.93) | 3079 (4.50) |
| Ethnicity | |||
| White | 45,472 (42.12) | 16,891 (42.79) | 28,581(41.73) |
| Black | 456 (0.42) | 167 (0.42) | 289 (0.42) |
| Chinese | 186 (0.17) | 73 (0.18) | 113 (0.16) |
| South Asian | 1145 (1.06) | 524 (1.33) | 621 (0.91) |
| Other | 150 (0.14) | 61 (0.15) | 89 (0.13) |
| Missing | 60,533 (56.09) | 21,760 (55.12) | 38,793 (56.64) |
| CKD stage (CKD-EPI eGFR, ml/min/1.73 m2) | |||
| 3a (45-59) | 62,251 (57.66) | 20,842 (52.80) | 41,409 (60.46) |
| 3b (30-44) | 35,312 (32.71) | 14,227 (36.04) | 21,085 (30.79) |
| 4 (15-29) | 9611 (8.90) | 4106 (10.40) | 5505 (8.04) |
| 5 (9-14) | 788 (0.73) | 301 (0.76) | 487 (0.71) |
| Comorbidities | |||
| Diabetes | 32,814 (30.39) | 20,187 (51.14) | 12,627 (18.44) |
| Hypertension | 77,075 (71.39) | 29,846 (75.61) | 47,229 (68.96) |
| Coronary heart disease | 28,382 (26.29) | 11,547 (29.25) | 16,835 (24.58) |
| Chronic heart failure | 11,946 (11.07) | 4621 (11.71) | 7325 (10.70) |
| Peripheral vascular disease | 8281 (7.67) | 3562 (9.02) | 4719 (6.89) |
| Cerebrovascular disease | 16,402 (15.19) | 5997 (15.19) | 10,405 (15.19) |
| Systemic lupus erythematosus | 349 (0.32) | 120 (0.30) | 229 (0.33) |
| Hematuria | 11,027 (10.21) | 4370 (11.07) | 6657 (9.72) |
| Renal stone/prostate disease | 8191 (7.59) | 3315 (8.40) | 4876 (7.12) |
| History of acute kidney injury | 4290 (3.97) | 1644 (4.16) | 2646 (3.86) |
| Medications | |||
| Calcineurin inhibitorb/lithium | 1462 (1.35) | 514 (1.30) | 948 (1.38) |
| ACR (mg/mmol), median (IQR) | 2.6 (1.0 to 9.2) |
ACR, albumin:creatinine ratio; BMI, body mass index; CKD, chronic kidney disease; CKD-EPI, Chronic Kidney Disease – Epidemiology Collaboration; eGFR, estimated glomerular filtration rate; IQR, interquartile range.
a
Values shown are n (%) unless otherwise stated.
b
Cyclosporine or tacrolimus.