Table 2.
Proportion and Number of Patients Fulfilling Referral Criteria From Primary to Specialty Care
| Criteria | ACR Available Within 1 Year of Index sCr % (95% CI) (n = 39,476) |
Any ACR Statusa % (95% CI) (n = 107,962) |
|---|---|---|
| NICE guideline | ||
| All criteria | 19.17 (18.78 – 19.56) (7566) b |
17.02 (16.79 – 17.24) (18,369) b |
| eGFR <30 ml/min/1.73 m2 | 11.16 (10.85 – 11.48) (4407) |
9.63 (9.46 – 9.81) (10,399) |
| ACR >30 mg/mmol with hematuria | 1.49 (1.37 – 1.61) (587) |
1.13 (1.07 – 1.20) (1221) |
| ACR >70 mg/mmol without diabetes | 1.64 (1.53 – 1.77) (647) |
1.87 (1.79 – 1.95) (2015) |
| eGFR sustained decrease | 8.83 (8.55 – 9.11) (3486) |
7.77 (7.62 – 7.94) (8394) |
| KFRE | ||
| 5-year risk >3% | 21.94 (21.54 – 22.36) (8663) |
18.20 (17.97 – 18.43) (19,649) |
ACR, albumin:creatinine ratio; CI, confidence interval; eGFR, estimated glomerular filtration rate; KFRE, kidney failure risk equation; NICE, National Institute of Health and Care Excellence; sCr, serum creatinine.
ACR available within 5 years of index sCr considered, further missing ACRs imputed using multiple imputation using chained equations.
Patients to be referred to specialist nephrology care based on individual NICE criteria do not add up to the total patients to be referred to specialist nephrology care based on the combination of individual NICE criteria. This is because some patients have two or more indications for referral based on the NICE 2014 guideline.