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NGF promotes the release of paracrine immunosuppressive molecules from MSCs under HG conditions. The concentrations of (A) TGF-β, (B) IL-10, (C) TNF-α and (D) IL-6 were detected by ELISA. Values are expressed as the mean ± standard deviation (n=6). *P<0.05 vs. HG; #P<0.05 vs. HG+NGF. TrkA, neurotrophic receptor tyrosine kinase 1; MSC, mesenchymal stem cell; NGF, nerve growth factor; HG, high glucose; LG, low glucose.
