Figure 2.

Microbiome diversity in treatment and placebo groups from 10 subjects (48 samples). (a) Alpha diversity. Total operational taxonomic units and Shannon indices versus weeks from starting vancomycin. The blue lines are mixed model estimates of the means for the placebo and the Vancomycin periods. Count data were rarefied to a depth of 800. (b) Beta diversity. Constrained correspondence analysis (CCA) of microbiome samples from subjects receiving weekly placebo or vancomycin over the course of the study. Count data were rarified to a depth of 800.