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. 2021 Jun 11;32(2):299–305. doi: 10.52312/jdrs.2021.64

Table 3. Results of studies investigating the relationship between ADAM12 (rs1871054 and rs3740199) polymorphisms and knee OA.

Study Population SNPs Pathologic findings Results in sex
Kerna et al. (2009) Estonian population rs3740199 PFKOA M (+)
    rs1871054 PFKOA F (-)
        M/F (-)
Kerna et al. (2013)* Estonian population rs1871054 Advance stage OA osteophyte formation M/F (+)
Wang et al. (2015) Chinese Han population rs3740199 PFKOA M/F (-)
    rs1871054    
Lou et al. (2014) Chinese Han population rs3740199 PFKOA M/F (-)
    rs1871054 PFKOA susceptibility M/F (+)
Poonpet et al. (2016) Thai population rs3740199 PFKOA susceptibility M (+)
        F (-)
OA: Osteoarthritis; SNPs: Single nucleotide polymorphisms; PFKOA: Patellofemoral knee osteoarthritis; M: Male; F: Female; * Study with different radiographic classification system in same population