Table 2.

Parameter estimate for the base model without the addition of covariates

Parameter	Mean estimate of the final model ± SE
Central volume (Vc) (L)	2.01 ± 0.023
Peripheral colume (Vp) (L)	3.32 ± 0.28
Clearance (CL) (L/h)	1.15 ± 0.022
Intercompartmenral clearance (Q) (L/h)	0.75 ± 0.044
Between subject variability associated with Vc (%)	105%
Between subject variability associated with CL (%)	60%
Shrinkage Eta Vd	0.22
Shrinkage Eta Cl	0.066
Additional error (mg/L)	0.28