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. 2021 Aug 6;10:106. doi: 10.1186/s40249-021-00887-4

Table 4.

Socio-demographic, obstetric and knowledge predictors of uptake of SP during pregnancy

Predictors Uptake of IPTp-SP cOR, 95% CI aOR, 95% CI P-value
Optimal N = 296 Sub-optimal N = 76
n (%) n (%)
Age category
 15–24 years 121 (40.9) 39 (51.3) Reference
 25–34 years 142 (48.0) 31 (40.8) 1.4, 0.8–2.4
  ≥ 35 years 33 (11.1) 6 (7.9) 1.8, 0.7–4.6
Marital status
 Unmarried 62 (20.9) 25 (32.9) Reference
 Married 234 (79.1) 51 (67.1) 1.8, 1.0–3.1 1.7, 0.9–3.1 0.09
Woman's Education level
 Primary 108 (36.5) 34 (44.8) Reference
 Secondary 145 (49.0) 33 (43.4) 1.4, 0.8–2.4
 Tertiary 43 (14.5) 9 (11.8) 1.3, 0.6–2.9
Woman's Employment status
 Not employed 193 (65.2) 59 (77.6) Reference
 Informal employment 82 (27.7) 13 (17.1) 1.8, 0.9–3.4 1.7, 0.9–3.3 0.85
 Formal employment 21 (7.1) 4 (5.3) 1.6, 0.5–4.9 1.4, 0.5–4.6 0.45
Religion
 Catholic 13 (4.4) 7 (9.2) Reference
 Protestant 282 (95.3) 68 (89.5) 2.2, 0.8–5.7 2.5, 0.9–7.0 0.08
 Muslim 1 (0.3) 1 (1.3) 0.5, 0.1–10.0 1.3, 0.1–25.3 0.87
Ward of Residence
 Busali 68 (23.0) 17 (22.4) Reference
 Wodanga 37 (12.5) 12 (15.8) 0.8, 0.3–1.8
 North Maragoli 24 (8.1) 7 (9.2) 0.9, 0.3–2.3
 Chavakali 52 (17.6) 12 (15.8) 1.1, 0.5–2.5
 Sabatia West 46 (15.5) 14 (18.4) 0.8, 0.3–1.7
 Lyaduywa Izava 69 (23.3) 14 (18.4) 1.2, 0.6–2.7
Residence
 Rural 224 (75.7) 63 (82.9) Reference
 Urban 72 (24.3) 13 (17.1) 1.6, 0.8–3.1 1.60, 8–3.1 0.62
Gestation age at 1st ANC visit
  ≤ 16 weeks 179 (60.5) 18 (23.7) Reference
  > 16 weeks 117 (39.5) 58 (76.3) 0.2, 0.1–0.4 0.4, 0.2–0.9 0.04a
Frequency of ANC visits
  < 4 visits 33 (11.2) 51 (67.1) Reference
  ≥ 4 visits 263 (88.8) 25 (32.9) 17.1, 9.4–31.2 16.7, 7.9–35.3  < 0.001a
Parity
 1 child 108 (36.5) 34 (44.7) Reference
 2 children 66 (22.3) 16 (21.1) 1.2, 0.6–2.3
 3+ children 122 (41.2) 26 (34.2) 1.5, 0.8–2.6
Experience of SP side effects
 No 154 (52.0) 43 (56.6) Reference
 Yes 142 (48.0) 31 (40.8) 1.3, 0.8–2.2
 Not applicable 0 2 (2.6) N/A
Knowledge of MiP dangers
 Unknowledgeable 89 (30.1) 23 (30.3) Reference
 Low knowledge 110 (37.2) 26 (34.2) 1.0, 0.6–1.9 0.7, 0.4–1.5 0.38
 Moderate knowledge 73 (24.6) 21 (27.6) 0.9, 0.5–1.8 0.6, 0.3–1.2 0.13
 Adequate knowledge 24 (8.1) 6 (7.9) 1.0, 0.4–2.8 0.5, 0.2–1.6 0.28
Knowledge of MiP prevention
 Unknowledgeable 4 (1.4) 1 (1.3) Reference
 Low knowledge 168 (56.7) 48 (63.2) 0.9, 0.1–8.0
 Moderate knowledge 104 (35.1) 24 (31.6) 1.1, 0.1–10.1
 Adequate knowledge 20 (6.8) 3 (3.9) 1.2, 0.1–13.7
Knowledge of IPTp-SP benefits
 Poor 50 (16.9) 27 (35.5) Reference
 Good 246 (83.1) 49 (64.5) 2.7, 1.5–4.6 2.4, 1.3–4.5  < 0.001a
Knowledge of IPTp-SP start
 Poor 252 (85.1) 66 (86.8) Reference
 Good 44 (14.9) 10 (13.2) 1.2, 0.6–2.5
Knowledge of optimal SP
 Poor 135 (45.6) 48 (63.2) Reference
 Good 161 (53.4) 28 (36.8) 2.0, 1.2–3.3 1.9, 1.1–3.4 0.03a

aStatistically significant result at 5% significance level. ANC: Antenatal care; CI: Confidence interval; cOR: Crude odds ratio; IPTp-SP: Intermittent preventive treatment of malaria in pregnancy with sulphadoxine pyrimethamine; MiP: Malaria in pregnancy; SP: Sulphadoxine pyrimethamine