Fig. 3.

LJF exerting its antibiofilm effect in the biofilm-infection mouse model. a Schematic representation of treatment regimen in the biofilm-infection mouse model. b Peripheral tissue of implanted catheters by HE staining. c The representative pictures of pathological changes. d The pathological changes of three groups were compared. The incidence of pathological changes and the severity of inflammation were assessed by four grades: Grade I: normal; grade II: hyperemia and swelling; grade III: hyperemia, swelling and adhesion; grade IV: abscess, bleeding and adhesion. e, f The statistics analysis and the representative picture of colony counting in each group. *P < 0.05, **P < 0.01, compared with corresponding control