Table-2. Formulations Designed by Design-Expert Software with Effervescent Bases.
| Formulations |
Citric acid
(mg) |
Na bicarbonate (mg) |
Friability
(%) |
Disintegration time (sec) |
| F 14 | 27.00 | 24.00 | 0.40 | 49 |
| F 15 | 9.00 | 24.00 | 0.31 | 72 |
| F 16 | 18.00 | 24.00 | 0.36 | 61 |
| F 17 | 9.00 | 35.00 | 0.32 | 69 |
| F 18 | 18.00 | 13.00 | 0.33 | 77 |
| F 19 | 18.00 | 35.00 | 0.33 | 58 |
| F 20 | 9.00 | 13.00 | 0.31 | 75 |
| F 21 | 27.00 | 13.00 | 0.37 | 64 |
| F 22 | 27.00 | 35.00 | 0.42 | 47 |