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. 2018 May 27;7:e936. doi: 10.22086/gmj.v0i0.936

Table-2. Formulations Designed by Design-Expert Software with Effervescent Bases.

Formulations Citric acid
(mg)
Na bicarbonate (mg) Friability
(%)
Disintegration time (sec)
F 14 27.00 24.00 0.40 49
F 15 9.00 24.00 0.31 72
F 16 18.00 24.00 0.36 61
F 17 9.00 35.00 0.32 69
F 18 18.00 13.00 0.33 77
F 19 18.00 35.00 0.33 58
F 20 9.00 13.00 0.31 75
F 21 27.00 13.00 0.37 64
F 22 27.00 35.00 0.42 47