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. 2018 May 27;7:e936. doi: 10.22086/gmj.v0i0.936

Table-3. Formulations Designed by Design-Expert Software with Superdisintegrant and Effervescent Bases.

Formulations Citric acid
(mg)
Na bicarbonate
(mg)
CP
(mg)
Friability
(%)
Disintegration time (sec)
F 23 24.00 48 4.00 0.36 32
F 24 24.00 48 7.00 0.37 21
F 25 36.00 48 4.00 0.39 25
F 26 12.00 48 10.00 0.38 22
F 27 12.00 48 7.00 0.36 28
F 28 36.00 48 7.00 0.39 21
F 29 24.00 48 10.00 0.40 18
F 30 36.00 48 10.00 0.41 12
F 31 12.00 48 4.00 0.36 35

CP: Crospovidone