Table-3. Formulations Designed by Design-Expert Software with Superdisintegrant and Effervescent Bases.
| Formulations |
Citric acid
(mg) |
Na bicarbonate
(mg) |
CP
(mg) |
Friability
(%) |
Disintegration time (sec) |
| F 23 | 24.00 | 48 | 4.00 | 0.36 | 32 |
| F 24 | 24.00 | 48 | 7.00 | 0.37 | 21 |
| F 25 | 36.00 | 48 | 4.00 | 0.39 | 25 |
| F 26 | 12.00 | 48 | 10.00 | 0.38 | 22 |
| F 27 | 12.00 | 48 | 7.00 | 0.36 | 28 |
| F 28 | 36.00 | 48 | 7.00 | 0.39 | 21 |
| F 29 | 24.00 | 48 | 10.00 | 0.40 | 18 |
| F 30 | 36.00 | 48 | 10.00 | 0.41 | 12 |
| F 31 | 12.00 | 48 | 4.00 | 0.36 | 35 |
CP: Crospovidone