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. Author manuscript; available in PMC: 2021 Aug 6.
Published in final edited form as: Cell Rep. 2020 Sep 15;32(11):108145. doi: 10.1016/j.celrep.2020.108145

Figure 5. CADM1, B4GALNT3, DOCK9, and GPR133 (aka Adgrd1) are genetic regulators of BMD.

Figure 5.

(A-D) All four genes have an eQTL in at least one tissue in the GTEx database that colocalizes with a proximal BMD GWAS association. (E-H) Knockout mice from the KOMP for each gene exhibit altered BMD (E) N control male = 816, N control female = 778, N KO male = 7 N KO female = 7; (F) N control male = 445, N control female = 459, N KO male = 8, N KO female = 8; (G) N control male = 1692, N control female = 1729, N KO male = 8, N KO female = 8; (H) N control male = 1477, N control female = 1466, N KO male = 7, N KO female = 7, see also Figures S3 and S4 and Table S1.