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. 2021 Aug 6;19:334. doi: 10.1186/s12967-021-03011-0

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — DDX27 promotes the stem cell-like properties of breast cancer cells. a, b High expression of DDX27 was positively related to OCT4 and SOX2. c DDX27 was significantly high expressed in MCF-7 MS and T47D MS. d SOX2 and OCT4 were up-regulated in DDX27 over-expressed cells by western blot. e Proliferation abilities of breast cancer cells by CCK-8 assay. f Migration abilities of breast cancer cells by the Transwell assay. g Migration abilities of breast cancer cells by the wound-healing assay. *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001