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. 2021 Aug 4;59(1):972–983. doi: 10.1080/13880209.2021.1948066

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© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — Cyc aggravates DSS-induced colitis. (A) Body weights recorded in the experimental period. (B) Body weight loss was reported in grams. (C) The DAI score. (D) Representative macroscopic images of colon tissues. (E) Colon length. (F) The histopathology score. (G) Representative images of the colonic sections stained with H&E (magnification × 200, scale bars = 50 µm). Data are presented as means ± S.D. (n = 6). DSS: dextran sulphate sodium; EDT: eriodictyol; Cyc: cyclopamine; *p < 0.05 and **p < 0.01 compared with the DSS group; #p < 0.05 and ##p < 0.01 compared with the EDT + Cyc group.