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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: Curr Protoc. 2021 Jul;1(7):e189. doi: 10.1002/cpz1.189

Table 2.

Example cardiovascular PGx phenotypes

Cardiovascular PGx Phenotype Trait or Disease State Cardiovascular Drug Drug Response
Blood Pressure Response to Thiazide Diuretics Change in Blood Pressure in Hypertension patients Thiazide Diuretic Post-treatment Blood Pressure - Pre-Treatment Blood Pressure
Bleeding Outcomes after treatment with Warfarin Atrial Fibrillation Warfarin Bleeding events after treatment with Warfarin
Myopathy after treatment with Simvastatin Hypercholesterolemia Simvastatin Myopathy after treatment with Simvastatin
Cardiovascular Outcomes after treatment with Clopidogrel Percutaneous Coronary Intervention Clopidogrel Cardiovascular Outcomes after treatment with Clopidogrel
Elevated Fasting Glucose after treatment with Thiazide Diuretics Hypertension Thiazide Diuretic Post-treatment Fasting Glucose - Pre-treatment Fasting Glucose
Cardiovascular Outcomes after treatment with Calcium Channel Blockers Hypertension Calcium Channel Blocker Difference in Cardiovascular Outcomes in patients treated with Calcium Channel Blockers compared to those not treated with Calcium Channel Blockers

PGx: Pharmacogenomics