Table 2.
Cardiovascular PGx Phenotype | Trait or Disease State | Cardiovascular Drug | Drug Response |
---|---|---|---|
Blood Pressure Response to Thiazide Diuretics | Change in Blood Pressure in Hypertension patients | Thiazide Diuretic | Post-treatment Blood Pressure - Pre-Treatment Blood Pressure |
Bleeding Outcomes after treatment with Warfarin | Atrial Fibrillation | Warfarin | Bleeding events after treatment with Warfarin |
Myopathy after treatment with Simvastatin | Hypercholesterolemia | Simvastatin | Myopathy after treatment with Simvastatin |
Cardiovascular Outcomes after treatment with Clopidogrel | Percutaneous Coronary Intervention | Clopidogrel | Cardiovascular Outcomes after treatment with Clopidogrel |
Elevated Fasting Glucose after treatment with Thiazide Diuretics | Hypertension | Thiazide Diuretic | Post-treatment Fasting Glucose - Pre-treatment Fasting Glucose |
Cardiovascular Outcomes after treatment with Calcium Channel Blockers | Hypertension | Calcium Channel Blocker | Difference in Cardiovascular Outcomes in patients treated with Calcium Channel Blockers compared to those not treated with Calcium Channel Blockers |
PGx: Pharmacogenomics