Recommendations for Aspirin Use

Referenced studies that support recommendations are summarized in Online Data Supplements 17 and 18.

COR	LOE	RECOMMENDATIONS
IIb	A	1. Low-dose aspirin (75–100 mg orally daily) might be considered for the primary prevention of ASCVD among select adults 40 to 70 years of age who are at higher ASCVD risk but not at increased bleeding risk (S4.6-1–S4.6-8).
III: Harm	B-R	2. Low-dose aspirin (75–100 mg orally daily) should not be administered on a routine basis for the primary prevention of ASCVD among adults >70 years of age (S4.6-9).
III: Harm	C-LD	3. Low-dose aspirin (75–100 mg orally daily) should not be administered for the primary prevention of ASCVD among adults of any age who are at increased risk of bleeding (S4.6-10).