Table 3:
Variant | Studya | BrainCloud Hippocampus eQTL Gene | BrainCloud Hippocampus eQTL P-valueb,c | BrainCloud DLPFC eQTL Gene | BrainCloud DLPFC eQTL P-Valueb | Braineac eQTL Gene | Braineac eQTL P-Valueb,d |
---|---|---|---|---|---|---|---|
rs300802 | Current | SH3YL1 | 4.70E-04 | SH3YL1 | 1 15E-03 | SH3YL1 | 7.20E-04 |
ACP1 | 0.012 | ACP1 | 8.50E-03 | ||||
FAM150B | 6.30E-03 | ||||||
rs300799 | Current | SH3 YL1 | 8.17E-04 | SH3YL1 | 9.67E-04 | SH3YL1 | 7.50E-04 |
ACP1 | 0.040 | ACP1 | 8.20E-03 | ||||
FAM150B | 6.20E-03 | ||||||
rs300797 | Both | SH3YL1 | 3.26E-04 | SH3YL1 | 7.39E-04 | SH3YL1 | 7.60E-04 |
ACP1 | 0.027 | ACP1 | 8.20E-03 | ||||
FAM150B | 6.20E-03 | ||||||
rs300793 | Current | SH3YL1 | 2.85E-04 | SH3YL1 | 1 78E-03 | SH3YL1 | 7.60E-04 |
ACP1 | 9.45E-03 | ACP1 | 8.20E-03 | ||||
FAM150B | 6.20E-03 | ||||||
rs300778 | Both | SH3YL1 | 9.42E-04 | SH3YL1 | 7.18E-04 | SH3YL1 | 7.60E-04 |
ACP1 | 8.20E-03 | ||||||
ACP1 | 0.018 | FAM150B | 6.20E-03 | ||||
rs436446 | GWAS | SH3YL1 | 3.98E-04 | SH3YL1 | 3 18E-03 | SH3YL1 | 7.60E-04 |
ACP1 | 0 014 | ACP1 | 8.20E-03 | ||||
FAM150B | 6.20E-03 | ||||||
rs300774 | GWAS | SH3 YL1 | 1.77E-04 | SH3YL1 | 2.00E-03 | SH3YL1 | 7.60E-04 |
ACP1 | 8.20E-03 | ||||||
ACP1 | 0.017 | FAM150B | 6.20E-03 | ||||
rs300773 | GWAS | SH3YL1 | 4.80E-04 | SH3YL1 | 2.78E-03 | SH3YL1 | 7.60E-04 |
ACP1 | 6.45E-03 | ACP1 | 8.20E-03 | ||||
FAM150B | 6.20E-03 |
eQTL, expression quantitative trait loci; GWAS, genome-wide association study; DLPFC, dorsolateral prefrontal cortex
Indicates whether the variant was identified in the current sequencing study, our GWAS, or both.
The p-values provided by both BrainCloud and Braineac are false discovery rate-corrected. For BrainCloud, the most significant probe from each brain region is listed. For Braineac, the most significant combined p-value from all brain regions and probes tested is listed.
The p-value for SH3YL1 is the top one listed. The p-value for ACP1 is the bottom one listed.
The p-value for SH3YL1 is the top one listed. The p-value for ACP1 is the middle one listed. The p-value for FAM150B is the bottom one listed.