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. 2021 Jul 22;224(Suppl 6):S647–S659. doi: 10.1093/infdis/jiab335

Figure 3.

Figure 3.

Correlation of ACE2 and TMPRSS2 expression within the same placenta. A, TMPRSS2 is significantly correlated with ACE2 in fetal male placentas (ρ = 0.43, P = .01, n = 34) but not female placentas (ρ = 0.14, P = .42, n = 34). B, In fetal male placentas, TMPRSS2 was significantly correlated with ACE2 in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–exposed pregnancies (ρ = 0.54, P = .02, n = 19) but not controls (ρ = 0.36, P = .19, n = 15). C, There was no significant correlation between ACE2 and TMPRSS2 expression in fetal female placentas in either cases (ρ = 0.23, P = .34, n = 19) or controls (ρ = 0.10, P = .73, n = 15). All ΔΔCt values for TMPRSS2 and ACE2 expression are normalized to female negative controls.