Table 3.

Required features by our pathologists for a viewing system in our workflows, including features that are not standard in digital slide viewers

Commonly required features for a viewing system by pathologists
1.	Integration	Be able to open WSI from different scanner vendors in one application, without installing additional software, on different operating systems (Windows, MacOS)
2.		Be able to open WSI from clinical systems (such as Cerner CoPathPlus and MPath) with 1 click, using single-sign-on, authenticated to see PHI such as label and macro images
3.		Be able to open WSI from research systems (eg, cBioPortal and PPBC) with one click, using single sign on and without exposing PHI
4.		Be able to send individual slides with annotation easily to an education portal, without exposing PHI
5.	Share and download	Be able to download images in an anonymized format for educational purposes
6.		Be able to easily share anonymized WSI and annotations with trainees
7.		Be able to easily share WSI among colleagues for consultations
8.	Annotate	Be able to assemble slide collections for education and research projects
9.		Be able to pixelwise annotate images and share annotations across research groups
10.	Efficiency and automation	Be efficient and do not lose performance (speed, image appearance)
11.		Be supported by automation tools such as measurement tools, screenshot tools, predefined mitotic count boxes, and others
12.		Be able to recognize reviewed slides and optionally reviewed areas on slides
13.		Be able to flip and rotate images and annotations
14.		Be able to review multiple slides side by side
15.		Be able to quickly detect poor quality scans and send them to rescan
16.	Ergonomics	Be able to efficiently navigate and annotate images with different input devices than a mouse

These features have been assessed in 2 feedback studies.

PHI: protected health information; PPBC: Precision Pathology Biobanking Center; WSI: whole slide images.