Figure 6.

Increased epigenetic age (EpiAge) is associated with decreased CD4 T cells. Flow cytometry was used to phenotype T cells from each individual included in the EpiAge analysis. Percent and absolute number of CD4 T cells were plotted against EpiAge. Simple linear regressions were generated to visualize the relationship. Multilinear regression analyses including age, sex, smoking status, and body mass index as covariables were used to determine if EpiAge had a significant impact on CD4 T-cell percent and absolute count. A Bonferroni correction was applied and P values below .025 were considered significant.