3D |
3-dimensional |
Ab |
antibody |
ADC |
antibody-drug conjugate |
AP-1 |
activator protein 1 |
AUC |
area under the curve |
Cl |
clearance |
CPM |
counts per minute |
CR |
complete regressor |
CT |
computed tomography |
DAR |
drug-to-antibody ratio |
DFO |
deferoxamine |
DOL |
degree of labeling |
FMT |
fluorescence molecular tomography |
HC |
heavy chain |
HPLC-MS |
high performance liquid chromatography–mass spectrometry |
IC50 |
half-maximal inhibitory concentration |
ID |
injected dose |
ID/g |
injected dose per gram |
IL13 |
interleukin 13 |
IR |
immuno-reactivity |
IV |
intravenous, intravenously |
JAK |
janus kinases |
LC |
light chain |
mAb |
monoclonal Ab |
MAPK |
mitogen-activated protein kinase |
MIP |
Maximum Intensity Projection |
PBS |
phosphate-buffered saline |
PET |
positron emission tomography |
PK |
pharmacokinetics |
PKB |
protein kinase B |
q4d |
every 4 days |
QC |
quality control |
R |
receptor |
ROI |
region of interest |
SEC |
size exclusion chromatography |
SEM |
standard error of the mean |
SNR |
signal-to-noise ratio |
SPECT |
single photon emission computed tomography |
STAT |
signal transducer and activator of transcription proteins |
T/C |
Tumor/control |
t1/2
|
half-life |
TGF |
transforming growth factor |
TNF |
tumor necrosis factor |
Zr |
zirconium |