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. 2021 Aug 4;13(1):1958662. doi: 10.1080/19420862.2021.1958662
Abbreviations Meaning
3D 3-dimensional
Ab antibody
ADC antibody-drug conjugate
AP-1 activator protein 1
AUC area under the curve
Cl clearance
CPM counts per minute
CR complete regressor
CT computed tomography
DAR drug-to-antibody ratio
DFO deferoxamine
DOL degree of labeling
FMT fluorescence molecular tomography
HC heavy chain
HPLC-MS high performance liquid chromatography–mass spectrometry
IC50 half-maximal inhibitory concentration
ID injected dose
ID/g injected dose per gram
IL13 interleukin 13
IR immuno-reactivity
IV intravenous, intravenously
JAK janus kinases
LC light chain
mAb monoclonal Ab
MAPK mitogen-activated protein kinase
MIP Maximum Intensity Projection
PBS phosphate-buffered saline
PET positron emission tomography
PK pharmacokinetics
PKB protein kinase B
q4d every 4 days
QC quality control
R receptor
ROI region of interest
SEC size exclusion chromatography
SEM standard error of the mean
SNR signal-to-noise ratio
SPECT single photon emission computed tomography
STAT signal transducer and activator of transcription proteins
T/C Tumor/control
t1/2 half-life
TGF transforming growth factor
TNF tumor necrosis factor
Zr zirconium