LncRNA CYTOR is highly expressed and may be related to L-OHP resistance in colon carcinoma cells
(a) Boxplot of lncRNA CYTOR expression level in normal group and tumor group in TCGA database. X-axis refers to sample types and Y-axis refers to lncRNA CYTOR relative expression. (b) qRT-PCR detected lncRNA CYTOR expression in 30 patients’ colon carcinoma tissue and adjacent tissue. (c) qRT-PCR detected lncRNA CYTOR expression in normal colon epithelial cells HCoEpiC and colon carcinoma cells HT-29, SW620 and HT55. (d) CCK-8 assay detected the proliferation of normal colon epithelial cells HCoEpiC and colon carcinoma cells HT-29, SW620 and HT55treated with different concentrations of L-OHP. (e) Subcellular location of lncRNA CYTOR (LINC00152) in 15 cell lines. CN RCI value as the standard. Positive value refers to cytoplasm location. Negative value refers to nucleus location. (f) Subcellular fractionation assay detected lncRNA CYTOR expression site in colon carcinoma cells. * denotes p < 0.05.