Figure 4.

LncRNA CYTOR stimulates L-OHP resistance and EMT of colon carcinoma cells via inhibiting miR-378a-5p

(a) qRT-PCR detected miR-378a-5p expression in HT-29 and SW620 cells in si-NC+NC-inhibitor, si-lncRNA CYTOR+NC-inhibitor and si-lncRNA CYTOR+miR-inhibitor groups. (b-c) CCK-8 detected proliferative ability of HT-29 and SW620 cells in each group with L-OHP of varying concentrations. (d-e) Cell viability of HT-29 and SW620 cells in different treatment groups after treatment with 10 μM L-OHP detected by CCK-8. (f) EMT-related protein (E-cadherin and N-cadherin) expression in HT-29 and SW620 cells in different treatment groups detected by western blot. * denotes p < 0.05.