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. 2021 Jul 22;9:681123. doi: 10.3389/fcell.2021.681123

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Copyright © 2021 Pazhayam, Turcotte and Sekelsky.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Chromatid interference. Each panel illustrates two crossovers on one bivalent, with each line representing one double-stranded DNA chromatid. The first (leftmost) crossover is the same in all cases, occurring between the two inner chromatids. (A) A 2-chromatid DCO. (B) Two possible 3-chromatid DCO configurations. (C) A 4-chromatid DCO. If there is no chromatid interference, the ratio of 2:3:4 should be 1:2:1.