Table 1.
Name | Description | Source |
---|---|---|
Population demographics and other-cause mortality | ||
Population demographic characteristics | Cross-sectional female population in US organized by birth cohorts | US census data (34) |
Other-case mortality | Death from other causes | CDC WONDER Database (41) |
Natural history | ||
Incidence in absence of screening | Breast cancer incidence in absence of screening and treatment | Age-period-cohort models (42, 43) |
Survival in absence of screening and treatment | 25-y breast cancer survival before adjuvant treatment by joint ER/HER2 status, age group, AJCC/SEER stage, or tumor size | Meta-analyses (44) |
Stage distribution | Stage distributions by mode of detection, age group (<50, 50-64, >65 y), screening round (first, subsequent), and screening interval | BCSC (40, 45) |
ER/HER2 joint distribution | Probability of ER/HER2 conditional on age and stage/tumor size at diagnosis | BCSC (40, 45) |
Screening and diagnosis | ||
Mammography rates | Use of mammography by different ages over time | NHIS, BCSC (40, 45, 46) |
Mammography performance | Sensitivity of initial and subsequent digital mammography by age group (<50, 50-64, >65 y) and screening interval | BCSC (40, 45) |
Treatment | ||
Treatment patterns | Treatments and rates of use by time period, ER/HER2, stage and age at time of breast cancer diagnosis | NCCN and meta-analyses (40, 47) |
Treatment effects | Treatment efficacy by ER/HER2 for initial breast cancer diagnosis | Meta-analyses and clinical trial results (48–53) |
AJCC = American Joint Committee on Cancer; BCSC = Breast Cancer Surveillance Consortium; CDC = Centers for Disease Control and Prevention; ER = estrogen receptor; HER2 = human epidermal growth factor receptor 2; NCCN = National Comprehensive Cancer Network; NHIS = National Health Information Survey; SEER = Surveillance, Epidemiology, and End Results; WONDER = Wide-ranging ONline Data for Epidemiologic Research.