TABLE. Demographic and clinical characteristics and laboratory test results among five skilled nursing facility residents with recurrent COVID-19 — Kentucky, 2020.
Patient | Sex (age group, yrs) | First outbreak (Jul–Aug) |
Second outbreak (Oct–Dec) |
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Ct values* | Symptoms | No. of days since positive test result in first outbreak | Ct values* | Symptoms | ||
A |
M (80–89) |
N1: 28.5 |
Asymptomatic |
101 |
N1: 30.0 |
Functional decline, lethargy, decreased appetite, dry cough; onset 1 day before test, persisted 14 days |
N2: 29.0 |
N2: 31.0 |
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RNAse P: 24.4 |
RNAse P: 32.0 |
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B |
F (80–89) |
N1: 28.2 |
Asymptomatic |
103 |
N1: 17.5 |
Congestion, SOB, respiratory failure; onset and hospitalization 1 day after test, death 8 days later |
N2: 28.8 |
N2: 19.1 |
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RNAse P: 25.8 |
RNAse P: 25.0 |
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104† |
E: 18.2 |
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N: 19.8 | ||||||
C |
F (60–69) |
N1: 28.9 |
Nausea at day 13 after positive test, persisted 1 day |
109 |
N1: 19.3 |
Cough, SOB, sore throat, loss of appetite, malaise, muscle aches; onset day of test, persisted 17 days |
N2: 28.9 |
N2: 20.4 |
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RNAse P: 24.9 |
RNAse P: 27.2 |
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D |
F (70–79) |
N1: 29.2 |
Gastrointestinal symptoms, onset 4 days prior to test, persisted 17 days, no fever or respiratory symptoms |
109 |
N1: 18.5 |
Loss of appetite, malaise; onset 3 days after test, persisted 12 days |
N2: 29.6 |
N2: 18.9 |
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RNAse P: 25.7 |
RNAse P: 22.2 |
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E | F (90–99) | N1: 28.9 |
Asymptomatic | 110 | N1: 17.2 |
Cough, loss of appetite, malaise, muscle aches; onset day of test, persisted 6 days |
N2: 29.9 |
N2: 17.9 |
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RNAse P: 33.0 | RNAse P: 21.1 |
Abbreviations: COVID-19 = coronavirus disease 2019; Ct = cycle threshold; F = female; M = male; RT-PCR = reverse transcription–polymerase chain reaction; SOB = shortness of breath.
* E and N genes are gene targets used to detect infection with SARS-CoV-2, the virus that causes COVID-19. One or both of the N1 and N2 gene targets must be detected with a Ct value ≤37 for a positive result. Lower Ct values indicate higher concentrations of SARS-CoV-2. RNAse P is a control that is used to assess specimen quality. Ct values ≤37 indicate the presence of human RNAse P gene.
† Patient B was retested with RT-PCR on hospital admission.