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. 2021 Jul 23;12:643480. doi: 10.3389/fneur.2021.643480

Table 3.

Multivariable models for the total sample (n = 686) and stratified by age.

Total sample 60–74 years ≥75 years
OR 95% CI* OR 95% CI* OR 95% CI*
Age
   60–74 years 1
   ≥75 years 2.75 1.70–4.46
Sex
   Male 1 1 1
   Female 1.45 0.84–2.51 1.14 0.61–2.14 2.33 0.73–7.42
Education
   ≥7 years of education 1 1 1
   0–6 years of education 0.52 0.27–1.00 0.45 0.22–0.91 1.81 0.26–12.72
Living area
   Suburban 1 1 1
   Rural 1.89 1.20–2.97 1.65 0.97–2.83 2.52 1.032–6.16
Income
   ≥Minimum wage 1 1 1
    < Minimum wage 0.96 0.46–2.01 0.93 0.38–2.28 0.98 0.22–4.36
   No income 1.36 0.54–3.39 1.38 0.44–4.27 1.28 0.21–7.69
Marital status
   Still married 1 1 1
   Single (never married/divorced) 1.71 1.03–2.84 1.53 0.85–2.276 2.80 0.89–8.877
Occupational class
   Professional 1 1 1
   Not working 2.18 1.03–4.60 2.98 1.21–7.31 1.02 0.22–4.65
   Laborer 2.19 0.94–5.10 3.65 1.29–10.30 0.23 0.03–1.93
   Housewife 1.89 0.64–5.56 2.43 0.68–8.71 0.87 0.06–12.43
Hypertension 1.12 0.73–1.73 1.10 0.66–1.81 1.29 0.52–3.20
Stroke 3.34 0.63–17.65 1.88 0.29–12.15
Diabetes 1.24 0.53–2.86 1.61 0.58–4.49 0.67 0.15–3.05
Triglyceride > 200 mg/dl 1.37 0.48–3.93 1.09 0.36–3.29
HDL <40 mg/dl 0.50 0.21–1.18 0.64 0.26–1.60 0.30 0.02–4.15
BMI characteristics
   Normal 1 1 1
   Underweight 1.30 0.78–2.19 1.49 0.80–2.80 1.25 0.48–3.26
   Overweight 0.39 0.18–0.82 0.40 0.17–0.91 0.38 0.06–2.43
   Obese 0.87 0.26–2.93 0.80 0.21–3.09 0.49 0.02–11.44
Smoking status 1.39 0.60–3.19 1.14 0.45–2.88 2.04 0.20–20.16
Depression 1.52 0.64–3.57 2.54 0.90–7.15 0.69 0.16–2.90
Leisure activities
   Intellectually less active 2.85 1.60–5.08 2.66 1.42–4.10 3.73 0.81–17.03
   Socially less active 1.38 0.89–2.13 1.53 0.92–2.53 1.06 0.41–2.74
   Recreationally less active 2.19 1.39–3.46 2.11 1.26–3.56 2.44 0.87–6.79
   Physically less active 2.05 0.99–4.25 1.87 0.83–4.20 2.57 0.45–14.65
   Less active (total leisure activity) 2.21 1.42–3.44 2.20 1.32–3.66 2.21 0.84–5.80
Dietary intake
   Non-frequent carbohydrate intake 1.13 0.74–1.74 1.30 0.78–2.15 1.03 0.43–2.45
   Non-frequent protein intake 0.80 0.52–1.25 0.94 0.56–1.57 0.56 0.23–1.39
   Non-frequent fruit intake 2.02 1.10–3.72 1.74 0.88–3.47 4.62 1.18–18.02
   Non-frequent vegetable intake 0.96 0.62–1.50 0.62 0.57–1.62 1.03 0.43–2.45

Multivariable models include age, sex, and education, plus all risk factors with ORs < 0.75 or >1.40 in the univariable models (Table 2).

OR, odds ratio; 95% CI, 95% confidence interval; HDL, high-density lipoprotein; BMI, body mass index.