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. Author manuscript; available in PMC: 2021 Aug 6.
Published in final edited form as: Acta Physiol (Oxf). 2020 May 18;229(4):e13478. doi: 10.1111/apha.13478

FIGURE 1.

FIGURE 1

Concentration-dependent 5-HT uptake clearance by the rat placenta from foetal circulation normalized to placental weight. Decreased clearance with increasing 5-HT concentration indicates the involvement of a saturable, transporter-mediated mechanism. Moreover at 1 and 10 nM 5-HT concentrations, we observe statistically significant differences in placental clearance between male and female placentas. Data presented are median + IQR (n > 3) for each sex/concentration. Statistical analysis was evaluated using non-parametric Mann-Whitney test: * (P ≤ .05)