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. Author manuscript; available in PMC: 2021 Aug 6.
Published in final edited form as: Acta Physiol (Oxf). 2020 May 18;229(4):e13478. doi: 10.1111/apha.13478

FIGURE 4.

FIGURE 4

Materno-foetal transport and metabolism of 5-HT in the rat term placenta. Analysis of concentration-dependent 5-HT transport in the materno-foetal direction before and after addition of phenelzine revealed a high degree of metabolism by MAO-A within the placenta and negligible transport across the trophoblast. Data are median + IQR of foetal/maternal concentration ratios with the insert displaying average foetal 5-HT concentrations at steady state just before and after addition of phenelzine (at minutes 20 and 50 respectively)